Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 expression in mice

1 suppresses the induction of UCP1 level in mice 2 Tomoya Sakamoto*, Takahiro Nitta*, Koji Maruno, 3 Yu-Sheng Yeh, Hidetoshi Kuwata, Koichi Tomita, Tsuyoshi 4 Goto , Nobuyuki Takahashi , and Teruo Kawada 3 5 1 Laboratory of Molecular Function of Food, Division of Food 6 Science and Biotechnology, Graduate School of Agriculture, 7 Kyoto University, Uji, Kyoto 611-0011, Japan 8 2 Center for Genetic Analysis of Behavior, National Institute for 9 Physiological Sciences, 5-1 Higashiyama, Myodaiji-cho, 10 Okazaki, Aichi 444-8787, Japan 11 3 Research Unit for Physiological Chemistry, the Center for the 12 Promotion of Interdisciplinary Education and Research, Kyoto 13 University, Uji, Kyoto, Japan 14 * These authors contributed equally to this work 15 16 Running title: Inflammation suppresses induction of UCP1 17 level in vivo 18 19 Correspondence: T. Kawada 20 Laboratory of Molecular Function of Food, Division of Food 21 Science and Biotechnology, Graduate School of Agriculture, 22 Kyoto University 23 Uji 51-0011, Japan 24 Articles in PresS. Am J Physiol Endocrinol Metab (February 16, 2016). doi:10.1152/ajpendo.00028.2015